Brain tumor diagnosis in hours: faster surgery and treatment

Researchers have developed a new testing method that could diagnose brain tumors within hours, potentially allowing treatment to begin during surgery.

A novel diagnostic technique using nanopore technology can reduce the wait time for brain tumor diagnosis from weeks to hours. Currently, patients undergo surgery where samples are taken and examined microscopically, but genetic testing—which can take eight weeks or more—is crucial for confirming tumor type. This new method sequences DNA rapidly by detecting disruptions in electric current as DNA strands pass through tiny pores. Tested on patient samples, it showed up to 90% accuracy within 24 hours and could classify many tumors within just one hour.

This speed could enable surgeons to adjust treatment during the operation and open possibilities for targeted drug delivery directly to tumors during surgery. The technique costs about £400 per sample, comparable to existing genetic tests. Experts highlight that faster diagnosis may also facilitate quicker patient enrollment in clinical trials and potentially transform intra-operative treatment approaches.

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