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Israeli and British scientists have developed a breakthrough blood test capable of detecting Parkinson’s disease in its earliest stages—before symptoms even begin—potentially revolutionizing diagnosis and treatment.
A joint team of researchers from Israel and the UK has unveiled a fast, affordable, and highly accurate blood test that can identify Parkinson’s disease long before clinical symptoms arise, The Press Service of Israel (TPS-IL) reports.
Parkinson’s, a progressive neurodegenerative disorder, affects over 10 million people globally and is notoriously difficult to diagnose early. By the time symptoms like tremors or stiffness appear, significant and often irreversible neurological damage has usually occurred.
The new test, based on qPCR technology, detects subtle changes in RNA fragments—specifically RGTTCRA-tRF—that are linked to the early development of the disease. This allows for pre-symptomatic diagnosis, enabling earlier interventions that could delay or even prevent disease progression.
The study was led by PhD student Nimrod Madrer and supervised by Prof. Hermona Soreq at the Hebrew University of Jerusalem, in collaboration with Dr. Iddo Paldor of the Shaare Zedek Medical Center and Dr. Eyal Soreq of the University of Surrey and Imperial College London. The findings were published in the journal Aging Nature.
The test could be particularly valuable for individuals with a family history of Parkinson’s, genetic risk factors, or early non-motor symptoms such as REM sleep behavior disorder. It could also aid pharmaceutical companies in selecting candidates for clinical trials targeting early-stage disease.
Beyond diagnosis, the test may help track the effectiveness of treatments by monitoring RNA fragment levels over time, giving clinicians a powerful tool to personalize therapy.
With broader clinical trials underway, the test could soon be available in community clinics, making early Parkinson’s screening widely accessible for the first time.
At least 69 people have died and almost 150 injured following a powerful 6.9-magnitude earthquake off the coast of Cebu City in the central Visayas region of the Philippines, officials said, making it one of the country’s deadliest disasters this year.
A tsunami threat was issued in Chile after a magnitude 7.8 earthquake struck the Drake Passage on Friday. The epicenter was located 135 miles south of Puerto Williams on the north coast of Navarino Island.
The war in Ukraine has reached a strategic impasse, and it seems that the conflict will not be solved by military means. This creates a path toward one of two alternatives: either a “frozen” phase that can last indefinitely or a quest for a durable political regulation.
A shooting in Nice, southeastern France, left two people dead and five injured on Friday, authorities said.
Snapchat will start charging users who store more than 5GB of photos and videos in its Memories feature, prompting backlash from long-time users.
The European Union is reportedly considering banning the use of ethanol as an active ingredient in biocidal products — including hand sanitisers — due to rising concerns about potential cancer risks, the Financial Times reported on Tuesday.
Johnson & Johnson (J&J) is facing its first lawsuits in the United Kingdom over claims that its talc-based products cause cancer, as it continues to battle tens of thousands of similar cases in the United States.
The World Health Organization on Monday issued a health advisory warning about three contaminated cough syrups identified in India, urging authorities to report any detection of these medicines in their countries to the health agency.
Around 6,000 students in Malaysia have been infected with influenza and some schools have been closed for the safety of children and staff, an education ministry official said.
Indian police have arrested the owner of Sresan Pharmaceutical Manufacturer, the cough syrup company linked to the deaths of at least 19 children in the central state of Madhya Pradesh, a senior police officer told Reuters on Thursday.
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