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Israeli and British scientists have developed a breakthrough blood test capable of detecting Parkinson’s disease in its earliest stages—before symptoms even begin—potentially revolutionizing diagnosis and treatment.
A joint team of researchers from Israel and the UK has unveiled a fast, affordable, and highly accurate blood test that can identify Parkinson’s disease long before clinical symptoms arise, The Press Service of Israel (TPS-IL) reports.
Parkinson’s, a progressive neurodegenerative disorder, affects over 10 million people globally and is notoriously difficult to diagnose early. By the time symptoms like tremors or stiffness appear, significant and often irreversible neurological damage has usually occurred.
The new test, based on qPCR technology, detects subtle changes in RNA fragments—specifically RGTTCRA-tRF—that are linked to the early development of the disease. This allows for pre-symptomatic diagnosis, enabling earlier interventions that could delay or even prevent disease progression.
The study was led by PhD student Nimrod Madrer and supervised by Prof. Hermona Soreq at the Hebrew University of Jerusalem, in collaboration with Dr. Iddo Paldor of the Shaare Zedek Medical Center and Dr. Eyal Soreq of the University of Surrey and Imperial College London. The findings were published in the journal Aging Nature.
The test could be particularly valuable for individuals with a family history of Parkinson’s, genetic risk factors, or early non-motor symptoms such as REM sleep behavior disorder. It could also aid pharmaceutical companies in selecting candidates for clinical trials targeting early-stage disease.
Beyond diagnosis, the test may help track the effectiveness of treatments by monitoring RNA fragment levels over time, giving clinicians a powerful tool to personalize therapy.
With broader clinical trials underway, the test could soon be available in community clinics, making early Parkinson’s screening widely accessible for the first time.
Video from the USGS (United States Geological Survey) showed on Friday (19 September) the Kilauea volcano in Hawaii erupting and spewing lava.
At least 69 people have died and almost 150 injured following a powerful 6.9-magnitude earthquake off the coast of Cebu City in the central Visayas region of the Philippines, officials said, making it one of the country’s deadliest disasters this year.
Authorities in California have identified the dismembered body discovered in a Tesla registered to singer D4vd as 15-year-old Celeste Rivas Hernandez, who had been missing from Lake Elsinore since April 2024.
A tsunami threat was issued in Chile after a magnitude 7.8 earthquake struck the Drake Passage on Friday. The epicenter was located 135 miles south of Puerto Williams on the north coast of Navarino Island.
A shooting in Nice, southeastern France, left two people dead and five injured on Friday, authorities said.
Indian police have arrested the owner of Sresan Pharmaceutical Manufacturer, the cough syrup company linked to the deaths of at least 19 children in the central state of Madhya Pradesh, a senior police officer told Reuters on Thursday.
More than 200 health facilities in war-hit eastern Congo have run out of medicines due to widespread looting and supply chain disruptions during fighting this year, the International Committee of the Red Cross (ICRC) said on Wednesday.
Indian authorities have launched a manslaughter investigation after at least 14 children died from a toxic cough syrup in Madhya Pradesh, raising fresh concerns over the country’s pharmaceutical safety.
U.S. President Donald Trump’s decision to impose 100% tariffs on branded and patented pharmaceuticals manufactured abroad poses a serious threat to Germany’s pharmaceutical sector, according to the Berlin-based industry group Verband Forschender Arzneimittelhersteller (vfa).
A flock of Canadian ostriches set to be culled, after two dead birds tested positive for avian flu, has been granted a last-minute stay of execution from Canada's highest court - for now.
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