Healthy UK babies born using DNA from three people to prevent genetic disorders

The Guardian

British researchers have announced a major scientific milestone: eight babies have been born healthy through a revolutionary technique that combines DNA from three individuals to eliminate the risk of passing on severe mitochondrial diseases.

The breakthrough, published in the New England Journal of Medicine and led by experts at Newcastle University and Monash University, could prevent conditions that lead to muscle weakness, organ failure, and even early death in children.

Out of 22 women who underwent the treatment, eight delivered healthy babies, and one is still pregnant.

Although the donor DNA comprises less than 1% of the baby’s genetic material — “too little to influence traits,” according to Dr. Lovell-Badge — the ethical and legal dimensions of altering embryos remain a point of debate.

Currently, the U.K. remains one of the only countries where such procedures are allowed, and only after strict approval by the Human Fertilisation and Embryology Authority. So far, 35 patients have been authorized to receive the treatment.

Critics argue the long-term effects are still unknown, especially for future generations.

Despite these uncertainties, for families facing heartbreaking diagnoses, this technique offers a new path forward.

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