A newly discovered bat coronavirus uses the same cell-surface protein to gain entry into human cells as the SARS-CoV-2 virus that causes COVID-19, raising the possibility that it could someday spread to humans, Chinese researchers have reported.
The virus does not enter human cells as readily as SARS-CoV-2 does, the Chinese researchers reported in the journal Cell, noting some of its limitations.
The scientists said that like SARS-CoV-2, the bat virus HKU5-CoV-2 contains a feature known as the furin cleavage site that helps it to enter cells via the ACE2 receptor protein on cell surfaces.
In lab experiments, HKU5-CoV-2 infected human cells with high ACE2 levels in test tubes and in models of human intestines and airways.
In further experiments, the researchers identified monoclonal antibodies and antiviral drugs that target the bat virus.
Bloomberg, which reported on the study earlier on Friday, said the paper identifying the bat virus had moved shares of COVID vaccine makers. Pfizer shares closed up 1.5% on Friday, Moderna climbed 5.3% and Novavax was up about 1% on a down day for the broader market.
Asked about concerns raised by the report of another pandemic resulting from this new virus, Dr. Michael Osterholm, an infectious disease expert at the University of Minnesota, called the reaction to the study "overblown."
He said there is a lot of immunity in the population to similar SARS viruses compared with 2019, which may reduce the pandemic risk.
The study itself noted that the virus has significantly less binding affinity to human ACE2 than SARS-CoV-2, and other suboptimal factors for human adaptation suggest the "risk of emergence in human populations should not be exaggerated."
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Afghanistan is facing a sharp increase in measles and other diseases, with over 12,500 new measles cases reported in March alone, as its strained health system struggles to respond amid declining international aid.
A highly accurate blood test that uses artificial intelligence to detect multiple cancers from just a few drops of blood is now entering clinical trials across the UK’s National Health Service.
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Afghanistan is facing a sharp increase in measles and other diseases, with over 12,500 new measles cases reported in March alone, as its strained health system struggles to respond amid declining international aid.
A highly accurate blood test that uses artificial intelligence to detect multiple cancers from just a few drops of blood is now entering clinical trials across the UK’s National Health Service.
On April 25, Azerbaijani President Ilham Aliyev met with OSCE Secretary General Feridun Sinirlioğlu to discuss the South Caucasus, peace talks with Armenia, and strengthening bilateral cooperation. Aliyev emphasized dismantling the OSCE Minsk Group and securing Azerbaijan’s sovereignty.
Hungarian Prime Minister Viktor Orban faces political challenges as U.S. tariffs threaten Hungary's economy. With opposition parties gaining momentum ahead of the 2024 elections, critics argue for a Europe-focused approach, criticizing Orban’s ties with Trump and his economic handling.
Indian security forces are conducting widespread searches across Kashmir after a deadly militant attack in Pahalgam killed 26 people, escalating tensions with Pakistan. India accuses Pakistan of backing the militants, though Islamabad denies involvement. Both nations have taken retaliatory measures,
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