Johnson & Johnson said on Thursday it will discontinue a late-stage study of an experimental E.coli vaccine it was developing in partnership with Sanofi.
The drugmaker said its decision was based on the recommendation of an independent committee that found the vaccine candidate may not be sufficiently effective compared with a placebo in preventing infections caused by a group of bacteria commonly found in the gut.
No safety signals related to the experimental vaccine were identified, J&J said, adding that it was conducting follow-ups for participants currently enrolled in the trial.
The study was testing the safety and efficacy of a single dose of the experimental shot, ExPEC9V, in preventing E.coli disease, including sepsis and blood infections.
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Details of a reported draft memorandum of understanding between the United States and Iran offer the clearest picture yet of how both sides plan to end months of conflict and move towards a longer-term settlement.
The U.S. and Iran say they have reached a deal to end their conflict, with an immediate ceasefire and reopening of the Strait of Hormuz after the lifting of the U.S. naval blockade. Talks will continue over the next 60 days to finalise the agreement
U.S. President Donald Trump has said a peace agreement with Iran is scheduled to be signed on Sunday in a post on social media, despite Tehran's Foreign Ministry spokesperson Esmaeil Baghaei saying no deal would be approved this weekend.
U.S. and Iranian officials said they had agreed on a framework to end their war, halt the U.S. blockade of Iran and reopen the Strait of Hormuz, a preliminary pact that sent oil prices falling but leaves the fate of Iran's nuclear program to further negotiations.
Switzerland on Sunday rejected a referendum proposal to cap its population at 10 million, a projection showed, as voters prioritised economic stability and the country's ties with the European Union over immigration concerns.
A U.S. doctor who contracted Ebola while on a humanitarian mission in the Democratic Republic of Congo has recovered and been discharged from a hospital in Germany, according to officials.
Protesters in Nanyuki blocked roads and burned tyres after residents challenged a U.S. plan to house Americans exposed to Ebola at a nearby military base.
Global health organisation CEPI will provide around $60 million to Moderna and two other partners to speed up the development of vaccines targeting the Ebola Bundibugyo strain, which is currently driving an outbreak in eastern Democratic Republic of Congo.
The head of the World Health Organization (WHO) has warned that the Ebola outbreak in the Democratic Republic of Congo may be significantly larger than official figures suggest, following a visit to the country where he briefed President Felix Tshisekedi on the ongoing response.
Four nurses have recovered and been discharged after receiving treatment for Ebola in the Democratic Republic of Congo, the World Health Organisation (WHO) said.
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