Iran has issued a sharp warning to Israel and the United States, threatening to take unspecified "special measures" to defend its nuclear facilities if threatened, just ahead of a new round of nuclear talks in Rome.

Iran’s Foreign Minister Abbas Araghchi warned on Thursday that his country would take “special measures” to defend its nuclear sites if threats from Israel continued. The warning followed a CNN report citing intelligence that Israel may be preparing to strike Iranian nuclear facilities. Israel has not confirmed such plans, but its leaders have repeatedly threatened action to prevent Iran from acquiring nuclear weapons.

In a letter to the United Nations Secretary-General, Araghchi said any Israeli action would be met with a decisive response and that Iran would hold the United States legally responsible as Israel’s main ally. He urged the international community to take preventive steps to stop Israeli threats.

Though Araghchi did not detail what steps Iran might take, he suggested their nature would depend on international response. In the past, Iranian officials have floated options such as limiting cooperation with the UN nuclear watchdog or relocating enriched uranium.

Separately, Iran’s Revolutionary Guards warned of a “devastating” response if Israel launches an attack.

The warnings come as Iran and the United States prepare for a fifth round of nuclear talks in Rome. Disagreements over uranium enrichment remain a key sticking point. Iran insists its nuclear programme is for civilian use, while U.S. and Israeli officials remain concerned about potential military aims.

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