Turkish FM to meet EU counterparts in Warsaw
Turkish Foreign Minister Hakan Fidan will travel to Warsaw on Thursday to attend an informal meeting of EU foreign ministers, focusing on regional security, hybrid threats, and Türkiye-EU cooperation.
Scientists in the UK have developed a super-strong antibody that could dramatically improve how the immune system attacks cancer cells by boosting its activation power.
Researchers at the University of Southampton have designed a new type of antibody that could strengthen the immune system’s ability to fight cancer. The team, supported by Cancer Research UK, discovered that by increasing the rigidity of antibodies - tiny proteins produced by white blood cells - they could trigger a much stronger immune response.
Antibodies work by attaching to harmful cells like bacteria, viruses, or cancer cells, marking them for attack by the immune system. The new prototype, which features extra structural bonds to stiffen its Y-shaped form, was found to outperform naturally occurring antibodies in lab tests.
“The concept of using immuno-stimulation for cancer treatment is very exciting,” said Professor Mark Cragg of the Centre for Cancer Immunology. “Even small increases in rigidity significantly improve how well antibodies can activate the immune system.”
Using supercomputers, the team visualized antibodies at atomic detail to precisely insert additional disulfide bonds—tiny bridges that stabilize the structure. This made the antibodies more rigid, allowing them to hold immune receptors closer together and produce a stronger activation signal.
PhD student Isabel Elliott explained: “Floppier antibodies are less effective at triggering immune cells. Rigid ones seem to organize the receptors better, leading to a more powerful response.”
Dr. Ivo Tews, Professor in Structural Biology, added that this strategy could be applied to a wide range of immune-related molecules, not just those used in cancer therapy.
Dr. Iain Foulkes, Executive Director of Research and Innovation at Cancer Research UK, emphasized the potential impact of the findings: “Refining how we harness the immune system is a vital step forward. These super-strong antibodies could empower new, more effective treatments for patients undergoing immunotherapy.”
The research is published in the journal Nature Communications, marking a promising step toward next-generation cancer treatments designed to supercharge the body’s natural defenses.
Kremlin spokesperson Dmitry Peskov has announced the upcoming release of a documentary film about Russian President Vladimir Putin.
ChatGPT has rapidly emerged as one of the most influential artificial intelligence tools, transforming how we interact with technology through natural language.
Discover every major VE Day 80 event in Britain, 5‑8 May 2025—from London’s parade and fly‑past to street parties, concerts and museum exhibitions.
New Tesla registrations in Denmark collapsed 67 % in April to 180 vehicles, industry data showed Thursday, underscoring a sharp demand drop for the EV maker in one of its once-strong European markets.
Chinese e-commerce platform Temu has announced it will no longer sell goods directly from China to U.S. customers, shifting instead to U.S.-based sellers amid the closure of a long-criticized customs loophole.
European Commission President Ursula von der Leyen unveiled a €500 million incentive package to enhance scientific research in Europe and attract leading researchers, particularly those from the U.S.
OpenAI announced Monday that it will retain its nonprofit governance structure while proceeding with a major restructuring of its for-profit subsidiary to enable greater capital-raising capacity amid intensifying competition in the artificial intelligence sector.
Fans of Rockstar Games' iconic franchise will need to exercise more patience, as the highly anticipated Grand Theft Auto VI has officially been delayed again—this time until May 26, 2026.
ChatGPT has rapidly emerged as one of the most influential artificial intelligence tools, transforming how we interact with technology through natural language.
Firefly Aerospace’s Alpha rocket suffered a technical failure after launch on Tuesday, causing a Lockheed Martin satellite to crash into the Pacific Ocean.
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