Rybelsus, an oral form of the GLP-1 drug semaglutide, has been discovered to provide similar cardiovascular benefits as the injectable forms of the drug.
Researchers presented this at the American College of Cardiology scientific meeting held in Chicago in March.
In a trial of 9,650 patients with type 2 diabetes, who had clogged heart arteries and/or chronic kidney disease, those taking Rybelsus were overall 14% less likely to experience heart-related death, heart attack or stroke than those who received a placebo after an average follow-up of four years.
Semaglutide, a glucagon-like peptide-1 receptor agonist, has been shown to reduce the risk of adverse cardiovascular events in patients with diabetes according to the New England Journal of Medicine.
The researchers saw a 26% reduction in non-fatal heart attacks with oral semaglutide and a 12% reduction in non-fatal strokes, both of which “are among the most common and devastating complications of diabetes,” study co author Dr. John Buse of the University of North Carolina School of Medicine said in a statement.
It is still unclear though the exact mechanism through which the drugs reduce cardiovascular risk is not known, however, their anti-inflammatory activity is thought to play a role.
“Semaglutide has been a mainstay of our efforts to reduce heart attack and stroke in people with diabetes,” Buse said. “Having an oral option to deliver this highly effective therapy is a big advance.”
Despite the resounding success of the drug manufactured alongside Ozempic, the injectable form by Pharma giant Novo Nordisk, the most common side effects mainly gastrointestinal problems such as nausea, diarrhea, constipation and gas remain.
Researchers have developed a new testing method that could diagnose brain tumors within hours, potentially allowing treatment to begin during surgery.
World leaders pledged over $170 million to WHO at the 2025 World Health Assembly in Geneva, reinforcing global support for multilateral health efforts.
Former U.S. President Joe Biden has been diagnosed with an aggressive form of prostate cancer, his office announced. The cancer has been identified with a Gleason score of 9, which, according to Cancer Research UK, indicates highly abnormal cells that are likely to grow rapidly.
Japanese children continue to struggle with mental health issues, ranking 32nd out of 43 developed and emerging countries, according to a new UNICEF report, despite notable improvements in education and strong physical health indicators.
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A delegation led by Yalchin Rafiyev, Deputy Minister of Foreign Affairs of the Republic of Azerbaijan and Chief Negotiator of COP29, participated in Climate Week in Panama, held from May 19–21, 2025, in Panama City.
Amazon continues to set the benchmark in logistics and operational excellence through its sophisticated inventory management techniques, enabling it to maintain a competitive edge and deliver exceptional customer service at scale.
Two staff members from the Israeli embassy in Washington, D.C., were shot and killed outside an event at the Capital Jewish Museum on Wednesday night, in what officials are calling a targeted and deeply disturbing act of violence. A suspect is currently in custody.
The U.S. government's decision in April 2025 to impose stricter export controls on advanced semiconductors has delivered a significant blow to Nvidia, compelling the company to obtain licenses for sales of its H20 AI chips to China—one of its largest and most strategically important markets.
Cryptocurrency exchange Coinbase has confirmed that at least 69,461 customers had personal and financial information stolen in a months-long data breach, which the company disclosed last week.
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Ukrainian President Volodymyr Zelenskyy met Turkish President Recep Tayyip Erdogan in Ankara on May 15, with discussions reportedly focusing on upcoming peace talks between Ukrainian and Russian delegates in Istanbul.
France has rejected India’s request to share source codes needed to integrate indigenous weapons into Rafale fighter jets. Despite repeated appeals, French manufacturer Dassault Aviation has refused to compromise on the issue
Ukrainian and Russian delegations meet behind closed doors at Istanbul’s Dolmabahçe Palace at 10:00 local time today to explore security guarantees, territorial integrity and a possible ceasefire.
AnewZ and Kazakhstan’s Jibek Joly/Silk Way TV channel co-hosted a special AnewZ Talks in Astana at Maqsut Narikbayev University (MNU), uniting global experts and young leaders at Silk Road Media Group’s journalism school to explore the growing intersection of media and diplomacy.
Researchers have developed a new testing method that could diagnose brain tumors within hours, potentially allowing treatment to begin during surgery.
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Matcha and coffee have both surged in popularity as go-to beverages for energy and potential health benefits. While coffee has long dominated the morning routine of many people worldwide, matcha-a powdered form of specially grown green tea-has emerged as a compelling alternative.
WHO Chief sounds alarm over widespread treatment gaps amid funding cuts.
A delegation led by Yalchin Rafiyev, Deputy Minister of Foreign Affairs of the Republic of Azerbaijan and Chief Negotiator of COP29, participated in Climate Week in Panama, held from May 19–21, 2025, in Panama City.
Amazon continues to set the benchmark in logistics and operational excellence through its sophisticated inventory management techniques, enabling it to maintain a competitive edge and deliver exceptional customer service at scale.
Two staff members from the Israeli embassy in Washington, D.C., were shot and killed outside an event at the Capital Jewish Museum on Wednesday night, in what officials are calling a targeted and deeply disturbing act of violence. A suspect is currently in custody.
The U.S. government's decision in April 2025 to impose stricter export controls on advanced semiconductors has delivered a significant blow to Nvidia, compelling the company to obtain licenses for sales of its H20 AI chips to China—one of its largest and most strategically important markets.
Cryptocurrency exchange Coinbase has confirmed that at least 69,461 customers had personal and financial information stolen in a months-long data breach, which the company disclosed last week.
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